Decoding host-microbe interactions with engineered human organoids
Meirelles and Persat**
EMBO Journal, 2025
Pseudomonas aeruginosa faces a fitness tradeoff between mucosal colonization and antibiotic tolerance during infections
Meirelles, Vayena, Debache, Schmidt, Distler, Rossy, Hatzimanikatis, Persat**
Nature Microbiology, 2024
Revitalizing antibiotic discovery and development through in-vitro modelling of in-patient infection conditions
Sollier, Basler, Broz, Dittrich, Drescher, Egli, Harms, Hierlemann, Hiller, King, McKinney, Moran-Gilad, Neher, Page, Panke, Persat, Picotti, Rentsch, Rivera-Fuentes, Sauer, Stolz, Tschudin-Sutter, van Delden, van Nimwegen, Veening, Zampieri, Zinkernagel, Khanna, Bumann, Jenal, Dehio**
Nature Microbiology, 2024
Bacteroides thetaiotaomicron metabolic activity decreases with polysaccharide molecular weight
Wong, Chillier, Fischer-Stettler, Zeeman, Battin and Persat**
mBio, 2024
Pseudomonas aeruginosa type IV pili actively induce mucus contraction to form biofilms in tissue-engineered human airways
Rossy, Distler, Meirelles, Pezoldt, Kim, Tala, Bouklas, Deplancke and Persat**
Plos Biology, 2023
Biofilm formation on human immune cells is a multicellular predation strategy of Vibrio cholerae
Vidakovic, Mikhaleva, Jeckel, Nisnevich, Strenger, Neuhaus, Raveendran, Ben-Moshe, Aznaourova, Nosho ,Drescher, Schmeck, Schulte, Persat, Avraham and Drescher**
Cell, 2023
Archaeal type IV pili stabilize Haloferax volcanii biofilms in flow
Odermatt, Nussbaum, Monnappa, Tala, Li, Sivabalasarma, Albers and Persat**
Current Biology, 2023
Fluid flow structures gut microbiota biofilm communities by distributing public goods
Wong, Fischer-Stettler, Zeeman, Battin and Persat**
PNAS, 2023
Pseudomonas aeruginosa mechanosensing controls cell polarity during twitching by activating two antagonistic response regulators
Kühn, Talà, Inclan, Patino, Al-Mayyah, MacMillan, Engel**, Persat**
EMBO Journal, 2023
Mechanoregulation of biofilm architecture promotes Pseudomonas aeruginosa antibiotic tolerance.
Cont, Vermeil and Persat**
mBio, 2023
Engineering Agrobacterium tumefaciens adhesion to target cells
Pierrat, Al-Mayyah and Persat**
ACS synthetic biology, 2022
KRAB zinc finger protein ZNF676 controls the transcriptional influence of LTR12-related endogenous retrovirus sequences
Iouranova, Grun, Rossy, Duc, Coudray, Imbeault, de Tribolet-Hardy, Turelli, Persat, Trono**
Mobile DNA, 2022
Mechanotaxis directs Pseudomonas aeruginosa twitching motility
Kühn, Talà, Inclan, Patino, Pierrat, Al-Mayyah, MacMillan, Negrete, Engel**, Persat**
PNAS, 2021
The wall-less bacterium Spiroplasma poulsonii builds a polymeric cytoskeleton composed of interacting MreB isoforms
Masson, Pierrat, Lemaitre**, Persat**
iScience, 2021
Time-Resolved Scanning Ion Conductance Microscopy for Three-Dimensional Tracking of Nanoscale Cell Surface Dynamics
Leitao, Drake, Pinjusic, Pierrat, Navikas, Nievergelt, Brillard, Djekic, Radenovic, Persat, Constam, Anders, Fantner**
ACS Nano, 2021
Monodisperse selectively permeable hydrogel capsules made from single emulsion drops
Steinacher, Cont, Du, Persat, and Amstad**
ACS Applied Materials & Interfaces, 2021.
The membrane microenvironment regulates the sequential attachment of bacteria to host cells
Pierrat, Wong, Al-Mayyah and Persat**
mBio, 2021
Dynamics and mechanics of type IV pili
Roadmap on emerging concepts in the physical biology of bacterial biofilms: from surface sensing to community formation
Kühn and Persat**
Physical Biology, 2021
Biofilms mechanically damage epithelia by buckling
Cont, Rossy, Al-Mayyah and Persat**
eLife, 2020
Article in Materials Today: Bacterial biofilms offer insights into the mechanobiology of infections
Selected for the Biomedical Picture of the Day by the MRC: Brute-force Biofilms
Mechanomicrobiology: how bacteria sense and respond to forces
Dufrene and Persat**
Nature Reviews Microbiology, 2020
Vibrio cholerae filamentation promotes chitin surface attachment at the expense of competition in biofilms
Wucher, Bartlett, Hoyos, Papenfort, Persat and Nadell**
PNAS, 2019
Highlighted in Nat. Rev. Microbiology: Settling down on chitin
Cellular advective-diffusion drives the emergence of bacterial surface colonization patterns and heterogeneity
Rossy, Nadell** and Persat**
Nature Communications, 2019
Article in Phys.org and Science Daily: How Flow Shapes Bacterial Biofilms
Pseudomonas aeruginosa orchestrates twitching motility by sequential control of type IV pili movements.
Talà, Fineberg, Kukura and Persat**
Nature Microbiology, 2019
Highlighted in Nat. Rev. Microbiology: Breaking Free of Labels
Article in The Scientist: How Bacteria “Walk” Across a Surface.
News and Views by Science Daily: Bacteria walk (a bit) like we do.
Article in Medindia: New Microscopy Visualizes Bacteria Motility.
Article on Radio Canada: Les bactéries marchent aussi...à leur façon.
Article in Le Scienze: I batteri si spostano (un po') come gli esseri umani
Article in Phys.org: How bacteria mobility is like human locomotion
Biofilms: flipping the switch
Pierrat and Persat**
eLife, 2017
Bacterial mechanotransduction
Persat**
Current Opinion in Microbiology, 2017
A periplasmic polymer curves Vibrio cholerae and promotes pathogenesis
Bartlett, Bratton, Duvshani, Miguel, Sheng, Martin, Nguyen, Persat, Desmarais, VanNieuwenhze, Huang, Zhu, Shaevitz, Gitai**.
Cell, 2017
An Ohmic model for electrokinetic flows of binary asymmetric electrolytes.
Persat**, Santiago**.
Current Opinion in Colloid & Interface Science, 2016
A scaffold protein connects type IV pili with the Chp chemosensory system to mediate activation of virulence signaling in Pseudomonas aeruginosa.
Inclan, Persat, Greninger, Von Dollen, Johnson, Krogan, Gitai, Engel**.
Molecular Microbiology, 2016
Type IV pili mechanochemically regulate virulence factors in Pseudomonas aeruginosa.
Persat, Inclan, Engel, Stone, Gitai**.
PNAS, 2015
The mechanical world of bacteria.
Persat, Nadell, Kim, Ingremeau, Siryaporn, Drescher, Wingreen, Bassler, Gitai**, Stone**.
Cell, 2015
Bacterial evolution: rewiring modules to get in shape.
Persat, Gitai**.
Current Biology, 2014
The curved shape of Caulobacter crescentus enhances surface colonization in flow.
Persat, Stone, Gitai**.
Nature Communications, 2014
MicroRNA profiling by simultaneous selective isotachophoresis and hybridization with molecular beacons.
Persat, Santiago**.
Analytical Chemistry, 2011
Quantification of global microRNA abundance by selective isotachophoresis.
Persat, Chivukula, Mendell, Santiago**.
Analytical Chemistry, 2010
Purification of nucleic acids from whole blood using isotachophoresis.
Persat, Marshall, Santiago**.
Analytical Chemistry, 2009
Basic principles of electrolyte chemistry for microfluidic electrokinetics. Part II: Coupling between ion mobility, electrolysis, and acid-base equilibria.
Persat, Suss, Santiago**.
Lab on a Chip, 2009
Basic principles of electrolyte chemistry for microfluidic electrokinetics. Part I: Acid-base equilibria and pH buffers.
Persat, Chambers, Santiago**.
Lab on a Chip, 2009
Electrokinetic control of sample splitting at a channel bifurcation using isotachophoresis.
Persat, Santiago**.
New Journal of Physics, 2009